Focused Libraries

In cooperation with MolTech (www.moltech.ru) Vitas-M Laboratory has expanded its product portfolio by adding a new service for our customers. We have created a focused library for Peroxisome Proliferator - Activated Receptor (PPAR-gamma) for you. We have screened our stock database, with >300,000 compounds, with Lead-Finder software. As a result of this Virtual Screening software we have selected 4,000 structures for a new PPAR-Gamma library. This library is called Lilac.

The Lilac PPAR-Gamma library is just a start for composing more focused libraries by means of the Lead-Finder software. We encourage you to send your requests concerning targets of interest of your. With the targets you provide we can create a focused library especially for your and your research efforts. We are open for any kind of co-operation in this area.

Why have we chosen to start with PPAR-Gamma? PPARs have been demonstrated to play a major role in a diverse group of processes and pathological conditions associated with aging, inflammation , immunity , obesity], diabetes , cancer , and fertility . About 5,000 scientific publications related to PPARs have been published. A specialized scientific journal PPAR Research was dedicated to highlight this area. In the article below you will find more information how the Lead-Finder software was used to make the selection for our PPAR-Gamma Focused Library.

PPAR-Gamma
Focused Library

 

Lilac: In this new series of Focused Libraries we have the following focused libraries:
PPAR-Gamma
PPAR-Alpha
PPAR-Delta
Dihydrofolate reductase
HMG-CoA reductase
Vitamin D receptor
Phospholipase A2
Thyroid hormone receptor Beta
Liver X receptor Alpha
Liver X receptor Beta
Dihydroorotate dehydrogenase
Leukotriene A4 hydrolase
Beta-lactamase
Estrogen receptor Beta
Farnesoid X receptor
Glucocorticoid receptor
Mineralocorticoid receptor
HIV-protease
Thyroid hormone receptor Alpha
Retinoic acid receptor Alpha
Retinoic acid receptor Gamma
Androgen receptor